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Beide Seiten der vorigen Revision Vorhergehende Überarbeitung Nächste Überarbeitung | Vorhergehende Überarbeitung Nächste Überarbeitung Beide Seiten der Revision | ||
pelargonium_sidoides_dc [2015/12/17 12:27] andreas |
pelargonium_sidoides_dc [2015/12/17 13:30] andreas |
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[Treatment of rats with the Pelargonium sidoides extract EPs® 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin., Koch, E., Biber, A., Phytomedicine, | [Treatment of rats with the Pelargonium sidoides extract EPs® 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin., Koch, E., Biber, A., Phytomedicine, | ||
- | The root extract (EPs® 7630) contained coumarins like umckalin, 6, | + | The root extract (EPs® 7630) contained coumarins like [[https:// |
"EPs® 7630 respectively the contained proanthocyanidins reduce the adhesiveness of group A streptococci by up to 47% (at an incubation concentration of 30 µg/ml). Here, the trihydroxylation of the B ring of the flavan-3-ol-subunits is of crucial importance for the activity, while the degree of polymerization plays a subordinate role. \\ | "EPs® 7630 respectively the contained proanthocyanidins reduce the adhesiveness of group A streptococci by up to 47% (at an incubation concentration of 30 µg/ml). Here, the trihydroxylation of the B ring of the flavan-3-ol-subunits is of crucial importance for the activity, while the degree of polymerization plays a subordinate role. \\ | ||
- | EPs® 7630 has a remarkably high inhibitory activity against neuraminidase (IC50 ca. 1 uGu/ml). The commercially available drugs zanamivir (IC50 ca. 18 µg/ml) and oseltamivir carboxylate (IC50 ca. 54 µg/ml) are considerably less active in the used in vitro model. The enzyme is significantly inhibited by proanthocyanidins, | + | EPs® 7630 has a remarkably high inhibitory activity against neuraminidase (IC50 ca. 1 µ/ml). The commercially available drugs zanamivir (IC50 ca. 18 µg/ml) and oseltamivir carboxylate (IC50 ca. 54 µg/ml) are considerably less active in the used in vitro model. The enzyme is significantly inhibited by proanthocyanidins, |
[Beitrag zur Kenntnis der Inhaltsstoffe und der Wirkung des Pelargonium sidoides Spezialextraktes EPs® 7630., Janecki, A., (Doctoral dissertation, | [Beitrag zur Kenntnis der Inhaltsstoffe und der Wirkung des Pelargonium sidoides Spezialextraktes EPs® 7630., Janecki, A., (Doctoral dissertation, | ||