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--- justicia_adhatoda_l [2015/11/17 12:57]
andreas
+++ justicia_adhatoda_l [2015/11/17 15:18]
andreas
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 Evergreen dense shrub of northern India, naturalized in India, Sri Lanka, Southeast Asia, up to 2.5m high, with unpleasant smell; stem bark yellowish; leaves simple, petioled, lanceolate to elliptic, entire; white flowers in axillary spikes; spikes with long peduncles; fruit a 4-seeded capsule, 2-2.5cm long, seeds 5-7mm in diameter.
-"The original home is the Himalayan region of northern India. Today, this plant is available worldwide in the plant trade." [[http://de.wikipedia.org/wiki/Indisches_Lungenkraut]]
+"This shrub has a number of traditional medicinal uses in Siddha Medicine, Ayurvedic and Unani systems of medicine." [[https://en.wikipedia.org/wiki/Justicia_adhatoda]]
 The leaves contain the quinazoline alkaloids deoxyvasicine, vasicine (0.96%) and vasicinone (0.03%). Vasicine undergoes auto-oxidation to vasicinone, but the rate is very low.\\
-"Vasicine has appreciable bronchodilatory effect and marked respiratory stimulant activities, whereas vasicinone shows relaxation of the tracheal muscle in vitro and bronchoconstriction in vivo. A detailed preclinical study revealed that vasicinone has a synergetic effect on vasicine in bronchodilation, as well as in increasing ciliary movements. It was also observed that the cardiac depressant effect manifested by vasicine was normalized by vasicinone. Vasicine and vasicinone mixed in 1 : 1 ratio has shown higher broncho-dilatory activity and antagonism against histamine induced bronchoconstriction as vasicine alone..."
+"Vasicine has appreciable bronchodilatory effect and marked respiratory stimulant activities, whereas vasicinone shows relaxation of the tracheal muscle in vitro and bronchoconstriction in vivo. A detailed preclinical study revealed that vasicinone has a synergetic effect on vasicine in bronchodilation, as well as in increasing ciliary movements. It was also observed that the cardiac depressant effect manifested by vasicine was normalized by vasicinone. Vasicine and vasicinone mixed in 1 : 1 ratio has shown higher broncho-dilatory activity and antagonism against histamine induced bronchoconstriction as vasicine alone..." \\
 [Quantitative determination of vasicine and vasicinone in Adhatoda vasica
 by high performance capillary electrophoresis. B. Avula, S. Begum, S. Ahmed, M. I. Choudhary, I.A.Khan, Pharmazie 63: 20-22 (2008)]
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 [Adhatoda vasica Nees: Phytochemical and Pharmacological Profile. Thokchom P Singh, Okram M Singh, Huidrom B Singh, The Natural Products Journal 01/2011; 1(29), 29-39]
 [[http://onlinelibrary.wiley.com/doi/10.1111/j.1527-3458.2007.00032.x/full]]
+{{:justicia_adhatoda.jpg?500}} \\
+Curtis’s Botanical Magazine, vol.22 t.861 (1805) [S.T.Edwards] \\
+[[http://plantgenera.org/species.php?id_species=571752]]

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