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justicia_adhatoda_l [2015/11/17 12:57] andreas |
justicia_adhatoda_l [2015/11/17 15:10] andreas |
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The leaves contain the quinazoline alkaloids deoxyvasicine, vasicine (0.96%) and vasicinone (0.03%). Vasicine undergoes auto-oxidation to vasicinone, but the rate is very low.\\ | The leaves contain the quinazoline alkaloids deoxyvasicine, vasicine (0.96%) and vasicinone (0.03%). Vasicine undergoes auto-oxidation to vasicinone, but the rate is very low.\\ |
"Vasicine has appreciable bronchodilatory effect and marked respiratory stimulant activities, whereas vasicinone shows relaxation of the tracheal muscle in vitro and bronchoconstriction in vivo. A detailed preclinical study revealed that vasicinone has a synergetic effect on vasicine in bronchodilation, as well as in increasing ciliary movements. It was also observed that the cardiac depressant effect manifested by vasicine was normalized by vasicinone. Vasicine and vasicinone mixed in 1 : 1 ratio has shown higher broncho-dilatory activity and antagonism against histamine induced bronchoconstriction as vasicine alone..." | "Vasicine has appreciable bronchodilatory effect and marked respiratory stimulant activities, whereas vasicinone shows relaxation of the tracheal muscle in vitro and bronchoconstriction in vivo. A detailed preclinical study revealed that vasicinone has a synergetic effect on vasicine in bronchodilation, as well as in increasing ciliary movements. It was also observed that the cardiac depressant effect manifested by vasicine was normalized by vasicinone. Vasicine and vasicinone mixed in 1 : 1 ratio has shown higher broncho-dilatory activity and antagonism against histamine induced bronchoconstriction as vasicine alone..." \\ |
[Quantitative determination of vasicine and vasicinone in Adhatoda vasica | [Quantitative determination of vasicine and vasicinone in Adhatoda vasica |
by high performance capillary electrophoresis. B. Avula, S. Begum, S. Ahmed, M. I. Choudhary, I.A.Khan, Pharmazie 63: 20-22 (2008)] | by high performance capillary electrophoresis. B. Avula, S. Begum, S. Ahmed, M. I. Choudhary, I.A.Khan, Pharmazie 63: 20-22 (2008)] |
[Adhatoda vasica Nees: Phytochemical and Pharmacological Profile. Thokchom P Singh, Okram M Singh, Huidrom B Singh, The Natural Products Journal 01/2011; 1(29), 29-39] | [Adhatoda vasica Nees: Phytochemical and Pharmacological Profile. Thokchom P Singh, Okram M Singh, Huidrom B Singh, The Natural Products Journal 01/2011; 1(29), 29-39] |
[[http://onlinelibrary.wiley.com/doi/10.1111/j.1527-3458.2007.00032.x/full]] | [[http://onlinelibrary.wiley.com/doi/10.1111/j.1527-3458.2007.00032.x/full]] |
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| {{:justicia_adhatoda.jpg?500}} \\ |
| Bentham-Moxon Trust.; Curtis, William; Curtis's botanical magazine dedications, 1827-1927, f.861 \\ |
| [[https://commons.wikimedia.org/wiki/File:Curtis's_botanical_magazine_%28No._861%29_%288471018664%29.jpg]] |