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- | Products of the twigs wih leaves (Hamamelidis folium et cortex) are used to treat diarrhea, as a gargle and mouth rinse for inflammation of the gums and throat, skin ailments including wounds, bruises and abrasions, varicose veins, and haemorrhoids. //Hamamelis water// is made by steam distillation with water to which ethanol is added. \\ | + | Products of the twigs wih leaves (Hamamelidis folium et cortex) are used to treat diarrhea, as a gargle and mouth rinse for inflammation of the gums and throat, skin ailments including wounds, bruises and abrasions, varicose veins, and haemorrhoids. //Hamamelis water// is made by steam distillation with water to which ethanol is added at the end. The product contains 15%(vol) ethanol and 10-80ppm essential oil.\\ |
- | [Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 164] | + | [Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 164] \\ |
+ | [Hagers Handbuch der Pharmazeutischen Praxis, Springer 2010] | ||
"A crude hydroalcoholic extract from Hamamelis virginiana bark was subjected to ultrafiltration (UF) with a cut-off limit of 3 kDa to obtain a higher and a lower molecular weight fraction. Characterisation of the fractions was attempted with TLC, HPLC, acidic hydrolysis, and chromatography over Sephadex LH-20. The UF-concentrate was shown to consist mainly of oligomeric to polymeric proanthocyanidins (PA). This fraction was found to exhibit significant antiviral activity against Herpes simplex virus type 1 (HSV-1)." | "A crude hydroalcoholic extract from Hamamelis virginiana bark was subjected to ultrafiltration (UF) with a cut-off limit of 3 kDa to obtain a higher and a lower molecular weight fraction. Characterisation of the fractions was attempted with TLC, HPLC, acidic hydrolysis, and chromatography over Sephadex LH-20. The UF-concentrate was shown to consist mainly of oligomeric to polymeric proanthocyanidins (PA). This fraction was found to exhibit significant antiviral activity against Herpes simplex virus type 1 (HSV-1)." | ||
[Antiviral and antiphlogistic activities of Hamamelis virginiana bark., Erdelmeier, C. A., Cinatl Jr, J., Rabenau, H., Doerr, H. W., Biber, A., Koch, E., Planta medica, Vol.62(3), 1996, 241-245] | [Antiviral and antiphlogistic activities of Hamamelis virginiana bark., Erdelmeier, C. A., Cinatl Jr, J., Rabenau, H., Doerr, H. W., Biber, A., Koch, E., Planta medica, Vol.62(3), 1996, 241-245] | ||
- | "n the present study, | + | "...the effects of tannins obtained from various plant sources on the activity of 5-LOX and AT were examined. With IC50 values ranging from 1.0 to 18.7 muM, hamamelitannin and the galloylated proanthocyanidins isolated from Hamamelis virginiana L. were found to be most potent inhibitors of 5-LOX." |
[Dual inhibitory activities of tannins from Hamamelis virginiana and related polyphenols on 5-lipoxygenase and lyso-PAF: acetyl-CoA acetyltransferase., | [Dual inhibitory activities of tannins from Hamamelis virginiana and related polyphenols on 5-lipoxygenase and lyso-PAF: acetyl-CoA acetyltransferase., | ||
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+ | "... volatile fractions were obtained by water distillation from the entire fresh leaves and freshly collected bark in 0.13 % and 0.09% yields, respectively, | ||
+ | ketones, cannot be confirmed by this study... For the bark and leaf distillation product, we found 6, | ||
+ | aldehydes, nonanal (2.72 %) and hexacosanal (0.91 %) were the main Hamamelis ketones in the bark and leaf distillate, respectively... Compounds with 13 carbons such as the vitispiranes, | ||
+ | and hydroxydihydroedulan are rare essential oil components, accounting for ca 0.4%. The diterpenes manoyloxide, | ||
+ | [Study on the composition of the volatile fraction of Hamamelis virginiana., | ||
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+ | "... two major classes of constituents, | ||
+ | [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin., Deters, A., Dauer, A., Schnetz, E., Fartasch, M., Hensel, A., Phytochemistry, | ||
"Witch hazel (Hammamelis virginiana) bark is a rich source of both condensed and hydrolizable oligomeric tannins... The high content in pyrogallol moieties may be behind the effect of witch hazel phenolics on skin cells." | "Witch hazel (Hammamelis virginiana) bark is a rich source of both condensed and hydrolizable oligomeric tannins... The high content in pyrogallol moieties may be behind the effect of witch hazel phenolics on skin cells." | ||
[Highly galloylated tannin fractions from witch hazel (Hamamelis virginiana) bark: electron transfer capacity, in vitro antioxidant activity, and effects on skin-related cells., Touriño, S., Lizárraga, D., Carreras, A., Lorenzo, S., Ugartondo, V., Mitjans, M., Torres, J.L., Chemical research in toxicology, Vol.21(3), 2008, 696-704] | [Highly galloylated tannin fractions from witch hazel (Hamamelis virginiana) bark: electron transfer capacity, in vitro antioxidant activity, and effects on skin-related cells., Touriño, S., Lizárraga, D., Carreras, A., Lorenzo, S., Ugartondo, V., Mitjans, M., Torres, J.L., Chemical research in toxicology, Vol.21(3), 2008, 696-704] | ||
- | {{http:// | + | {{:hamamelis_virginiana.jpg?500}} \\ |
Köhler, F.E., Medizinal Pflanzen, vol. 3: t. 39 (1890) \\ | Köhler, F.E., Medizinal Pflanzen, vol. 3: t. 39 (1890) \\ | ||
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