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Beide Seiten der vorigen Revision Vorhergehende Überarbeitung Nächste Überarbeitung | Vorhergehende Überarbeitung Nächste Überarbeitung Beide Seiten der Revision | ||
centaurium_erythraea_rafn [2015/03/12 09:30] andreas |
centaurium_erythraea_rafn [2016/05/07 09:46] andreas |
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Annual or biennial herb, up to 50cm high, native to Eurasia, Central Asia, North Africa, naturalized in North America; leaves basal, oblong (first year); flowers wheel-shaped, | Annual or biennial herb, up to 50cm high, native to Eurasia, Central Asia, North Africa, naturalized in North America; leaves basal, oblong (first year); flowers wheel-shaped, | ||
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+ | The dried aerial parts of C.erythraea are difficult to distinguish from other Centaurium species. They are used as bitter tonic to increase gastric juice production, to treat dyspeptic disorders and loss of appetite. The flowers have better bitterness values (6000-12000) than leaves (1300-3800) and stems (600-1200), so a high content of flowers is preferred. The secoiridoid glucosides centapicrin and desacetylcentapicrin, | ||
+ | [Kommentar zum DAB10, 1993] \\ | ||
+ | [Hagers Handbuch der Pharmazeutischen Praxis, Springer 2010] | ||
Swertiamarin and sweroside, isolated from the aerial parts of Centaurium erythraea, "... inhibited the growth of Bacillus cereus, Bacillus subtilis, Citrobacter freundiiand Escherichia coli. While swertiamarin was also active against Proteus mirabilis and Serratia marcescens, sweroside inhibited the growth of Staphylococcus epidermidis." | Swertiamarin and sweroside, isolated from the aerial parts of Centaurium erythraea, "... inhibited the growth of Bacillus cereus, Bacillus subtilis, Citrobacter freundiiand Escherichia coli. While swertiamarin was also active against Proteus mirabilis and Serratia marcescens, sweroside inhibited the growth of Staphylococcus epidermidis." | ||
[Bioactivity of secoiridoid glycosides from Centaurium erythraea., Kumarasamy, Y., Nahar, L., Cox, P. J., Jaspars, M., Sarker, S.D., Phytomedicine, | [Bioactivity of secoiridoid glycosides from Centaurium erythraea., Kumarasamy, Y., Nahar, L., Cox, P. J., Jaspars, M., Sarker, S.D., Phytomedicine, | ||
- | The dried aerial parts are used as bitter tonic to treat dyspepsia. \\ | ||
"A bitter tonic to treat digestive disturbances, | "A bitter tonic to treat digestive disturbances, | ||
The plant contains bitter iridoid glycosides, so-called secoiridoids - mainly swertiamarin but also gentiopicrin, | The plant contains bitter iridoid glycosides, so-called secoiridoids - mainly swertiamarin but also gentiopicrin, | ||
[Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 89] | [Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 89] | ||
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+ | "The use of Centaurium erythraea Rafn has a long tradition in Europe, mainly in mild dyspeptic/ gastrointestinal disorders and in temporary loss of appetite... The medicinal use has been documented continuously in well-known handbooks... The pharmacological activity is attributed to the whole extract; however emphasis is put on the group of secoiridoid glycosides (‘bitters’) with main components swertiamarin, | ||
+ | to the pharmacological activity of Centaurii herba... There are no clinical safety data for extracts of Centaurii herba. In the documentation of the traditional medicinal use within the Community, no serious adverse effects have been reported." | ||
+ | [Assessment report on Centaurium erythraea Rafn s. L. including C. majus (H. et L.) Zeltner and C. suffruticosum (griseb.) Ronn., herba, for the development of a community herbal monograph, 2009] \\ | ||
+ | [[http:// | ||
The methanolic extract (ultrasonic maceration, freeze-dried, | The methanolic extract (ultrasonic maceration, freeze-dried, | ||
- | "The short-term (12 days) treatment of the STZ-diabetic rats with CE-extracts resulted in a 74% reduction of the produced hyperglycemia, | + | "The short-term (12 days) treatment of the STZ-diabetic rats with CE-extracts resulted in a 74% reduction of the produced hyperglycemia, |
[Chemical characterization of Centaurium erythrea L. and its effects on carbohydrate and lipid metabolism in experimental diabetes., Stefkov, G., Miova, B., Dinevska-Kjovkarovska, | [Chemical characterization of Centaurium erythrea L. and its effects on carbohydrate and lipid metabolism in experimental diabetes., Stefkov, G., Miova, B., Dinevska-Kjovkarovska, | ||
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+ | "The aqueous extract of E. centaurium, administered to merione at 200 mg/kg for 6 months produced a significant reduction in glycemia, insulinemia, | ||
+ | [Effect of Aqueous Extract from Erythrea Centaurium in Merione Shawi., Zaid, A., Int J Diabetol Vasc Dis Res, Vol.2(8), 2014, 1-5] \\ | ||
+ | [[http:// | ||
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Fuchs, L., New Kreüterbuch, | Fuchs, L., New Kreüterbuch, | ||
[[http:// | [[http:// | ||
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+ | Centaurium erythraea, [[https:// |