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Nächste Überarbeitung | Vorhergehende Überarbeitung Nächste Überarbeitung Beide Seiten der Revision | ||
carapichea_ipecacuanha_brot._l.andersson [2016/01/13 12:43] andreas angelegt |
carapichea_ipecacuanha_brot._l.andersson [2016/01/14 17:22] andreas |
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ipecacuanha, | ipecacuanha, | ||
- | Evergreen shrub, up to 40cm high, native to South America, Central America, also cultivated; flowers small, white, | + | Evergreen shrub, up to 40cm high, native to South America, Central America, also cultivated; root knotty, with transverse rings; leaves opposite, simple, elliptic, acuminate; flowers small, white, |
Cephaelis acuminata H.Karst. (syn. Uragoga granatensis Baillon) also known as Cartagena-Ipecacuanha, | Cephaelis acuminata H.Karst. (syn. Uragoga granatensis Baillon) also known as Cartagena-Ipecacuanha, | ||
- | Ipecac roots are used because of their expectorant, | + | When the ipecac alkaloids cephaeline, emetine and the synthetic 2-dehydroemetine (as dihydrochlorides) were administered to rabbits and cats, the effects of the three alkaloids on respiratory tract were identical. The volume output of respiratory tract fluid was increasingly augmented by doses of from 0.1 to 1.0 mg/kg. Doses of from 9.0 to 81 mg/kg were increasingly lethal. \\ |
+ | [The expectorant action of cephaeline, emetine and 2‐dehydroemetine., | ||
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+ | Ipecac roots are used because of their expectorant, | ||
+ | At about 10 times the therapeutic dose of ipecac extract used to treat chronic bronchitis, it is strongly emetic. The extract is used in emetic syrups to induce vomiting in case of accidental poisoning. As [[https:// | ||
[Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 259] | [Medicinal Plants of the World. Ben-Erik Van Wyk and Michael Wink, Pretoria 2004, 259] | ||
+ | {{: | ||
- | + | The isoquinoline alkaloids emetine and cephaeline, identified as the major bioactive compounds, | |
- | The isoquinoline alkaloids emetine and cephaeline | + | |
[Variation in emetine and cephaeline contents in roots of wild ipecac (Psychotria ipecacuanha)., | [Variation in emetine and cephaeline contents in roots of wild ipecac (Psychotria ipecacuanha)., | ||
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[Clonal diversity and conservation genetics of the medicinal plant Carapichea ipecacuanha (Rubiaceae)., | [Clonal diversity and conservation genetics of the medicinal plant Carapichea ipecacuanha (Rubiaceae)., | ||
+ | "... HIV-1 RT [Reverse Transcriptase] was blocked in the presence of emetine in both models: in vitro reactions with isolated HIV-1 RT and intravirion, | ||
+ | [Natural Plant Alkaloid (Emetine) Inhibits HIV-1 Replication by Interfering with Reverse Transcriptase Activity., Valadão, A.L.C., Abreu, C.M., Dias, J.Z., Arantes, P., Verli, H., Tanuri, A., de Aguiar, R.S., Molecules, 20(6), 2015, 11474-11489] [[http:// | ||
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+ | {{: | ||
+ | Carapichea ipecacuanha (Brot.) L.Andersson as Psychotria ipecacuanha \\ | ||
+ | Kohl,F.G., Die officinellen Pflanzen der Pharmacopoea Germanica, t.144 (1891-1895) \\ | ||
+ | [[http:// |