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asarum_europaeum_l [2015/07/01 21:50]
andreas 		asarum_europaeum_l [2016/02/10 11:46]
andreas
Zeile 12: Zeile 12:
 [BI-Lexikon Heilpflanzen und Drogen, Ennet D., Leipzig 1990, 134]  [BI-Lexikon Heilpflanzen und Drogen, Ennet D., Leipzig 1990, 134] 
  
-A.europaeum essential oil of Romanian origin showed concentrations of 460–510 μg ml−1 for α-asarone (= (E)-asarone) and 24–29 μg ml−1 for β-asarone (= (Z)-asarone). \\+A.europaeum essential oil of Romanian origin showed concentrations of 460-510 μg/ml for α-asarone (= (E)-asarone) and 24-29 μg/ml for β-asarone (= (Z)-asarone). \\
 [Comparison of GC-MS and TLC techniques for asarone isomers determination., Oprean, R., Tamas, M., Roman, L., Journal of pharmaceutical and biomedical analysis, 18(1), 1998, 227-234] [Comparison of GC-MS and TLC techniques for asarone isomers determination., Oprean, R., Tamas, M., Roman, L., Journal of pharmaceutical and biomedical analysis, 18(1), 1998, 227-234]
  
Zeile 20: Zeile 20:
 The dried rhizome (Radix Asari, Rhizoma Asari, Asari radix, Haselwurzwurzel) owns a spicy, camphor-like odor and pepper-like, spicy, bitter taste. Pulverized material serves as sneezing powder. The drug contains an essential oil (0.7-4.1% dry weight, rootlets 2.1%) with variable composition. Main constituents are (E)-asarone (0.5-70%), (E)-methyl isoeugenol (0.5-40%), and [[http://www.flavornet.org/info/5273-85-8.html|(E)-isoelemicin]] (0.5-45%). \\ The dried rhizome (Radix Asari, Rhizoma Asari, Asari radix, Haselwurzwurzel) owns a spicy, camphor-like odor and pepper-like, spicy, bitter taste. Pulverized material serves as sneezing powder. The drug contains an essential oil (0.7-4.1% dry weight, rootlets 2.1%) with variable composition. Main constituents are (E)-asarone (0.5-70%), (E)-methyl isoeugenol (0.5-40%), and [[http://www.flavornet.org/info/5273-85-8.html|(E)-isoelemicin]] (0.5-45%). \\
 [Hagers Handbuch der Pharmazeutischen Praxis, Springer 2010]   [Hagers Handbuch der Pharmazeutischen Praxis, Springer 2010]  
 +
 +In 2010, the use of all plants belonging to the Asarum species in drugs was banned in Germany by decree of the Federal Institute for Drugs and Medical Devices (BfArM). The cause of this was the detection of aristolochic acid I in homeopathic mother tinctures of Asarum europaeum with approximately 0.044 - 0.13 ppm, and of Asarum canadense with approximately 127.4g/kg (about 0.13 ppm). \\
 +[[http://www.bfarm.de/SharedDocs/Downloads/DE/Arzneimittel/Pharmakovigilanz/Risikoinformationen/RisikoBewVerf/a-f/aristolochia_bescheid.pdf?__blob=publicationFile&v=2]]
  
 {{:asarum_europaeum.jpg?500}} \\ {{:asarum_europaeum.jpg?500}} \\
 Thomé,O.W., Flora von Deutschland Österreich und der Schweiz, Tafeln, vol.3 t.456 (1885) \\ Thomé,O.W., Flora von Deutschland Österreich und der Schweiz, Tafeln, vol.3 t.456 (1885) \\
 [[http://plantgenera.org/species.php?id_species=95879]] [[http://plantgenera.org/species.php?id_species=95879]]
asarum_europaeum_l.txt · Zuletzt geändert: 2017/01/02 17:57 von andreas

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