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--- asarum_europaeum_l [2015/07/01 21:32]
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+++ asarum_europaeum_l [2015/07/01 21:50]
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 Prostrate evergreen perennial, up to 10cm high, with a creeping branched rhizome, native to Central and South Europe; whole plant tomentose; stems short, developing in spring, each with two leaves; leaves leathery, shiny dark green, reniform (kidney-shaped), stalkes reddish brown; flowers solitary, axillary, dark purple-brown, campanulate; fruit a many-seeded capsule.
-The anaesthetic activity of trans-isoasarone and trans-isoeugenol methyl ether, both phenylpropanoids of A.europaeum, were measured in comparison to the unsubstituted propenyl benzene and to the mono methoxy derivative trans-anethole resp. benzocaine. Trans-isoasarone showed local anaesthetic activity with an intensity nearly equal to benzocaine. \\
+The anaesthetic activity of (E)-asarone (= α-asarone, trans-isoasarone) and (E)-methyl isoeugenol (isoeugenol methyl ether), both phenylpropanoids of A.europaeum, were measured in comparison to the unsubstituted propenyl benzene and to the mono methoxy derivative trans-anethole resp. benzocaine. (E)-asarone showed local anaesthetic activity with an intensity nearly equal to benzocaine. \\
 [The Active Substances of Asarum europaeum., Gracza, L., Planta medica, 48(7), 1983, 153-157]
-"Extracts of the drug produce nausea, laxative and diuretic. In former times, the rhizome was used as emetic and sneezing powder. The root was used in folk medicine to treat diseases of the kidney, bladder, liver, and inflammation of the upper respiratory tract. The use of the decoction is not encouraged, as side effects can not be excluded." \\
+{{:isoeugen_asa.jpg|}} (E)-asarone (R=OCH3, α-asarone) or (E)-methyl isoeugenol (isoeugenol methyl ether, R=H)
+"The locally strong irritant effect and the pepper-like burning taste of the drug is ascribed to trans-isoasarone... Extracts of the drug cause vomit, laxative and diuretic. In former times, the rhizome was used as emetic and sneezing powder. The root was used in folk medicine to treat diseases of the kidney, bladder, liver, and inflammation of the upper respiratory tract. Further application of the decoction is not encouraged, as side effects can not be excluded." \\
 [BI-Lexikon Heilpflanzen und Drogen, Ennet D., Leipzig 1990, 134]

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